hrp0094p2-481 | Thyroid | ESPE2021

A case of hypothyroidism post bone marrow transplantation

Baz Ouidad , Chelghoum Imane Lydia , Mimouni Safia

Introduction: Changes in thyroid function and thyroid function tests occur in patients with β-thalassemia major (TM). The frequency of hypothyroidism in TM patients ranges from 4% to 29 % in different reports. Bone marrow transplantation (BMT) is based on destruction of the patient’s bone marrow with rescue of haematopoietic stem cells from a donor. Chronic graft-vs-host disease (GVH) is the major complication post-BMT and mimics some autoimmune diseases, such as ...

hrp0089p3-p223 | Growth & Syndromes P3 | ESPE2018

Coeliac Disease in Turner Syndrome More Frequent Than Expected

Ouidad Baz , Mourad Semrouni , Samia Sakher , Zerguini Safia Mimouni

Abstract: The risk of developing coeliac disease (CD) is higher in Turner syndrome (TS) than the general population, and screening has been recommended in asymptomatic individuals known to have an increased risk of developing the disease. In light of this recommendation, the aim of the study was to assess prevalence of celiac disease in Turner syndrome.Patients and methods: Serological screening of coeliac disease were performed in 85 children and adoles...

hrp0094p2-366 | Pituitary, neuroendocrinology and puberty | ESPE2021

Hypothalamic obesity in children with craniopharyngioma

Baz Ouidad , Achir Samia , Tazibt Oulebsir , Mimouni Safia ,

Introduction: Lesional hypothalamic obesity is most frequently attributable to craniopharyngiomas. The aim of our work is to describe the modalities of occurrence of this complication in a series of 27 children with craniopharyngioma followed in our center. We carried out a descriptive retrospective study of 27 cases of craniopharyngioma in children followed in the endocrinology department of the CPMC over a period of 16 years.Re...

hrp0094p2-351 | Pituitary, neuroendocrinology and puberty | ESPE2021

Growth hormone deficiency in 52 children with brain Magnetic Resonance Imaging Abnormalities

Baz Ouidad , Lydia Chelghoum Imane , Kafi Imane , Kafi Salima , Mimouni Safia ,

Growth Hormone (GH) deficiency is the most common pituitary hormone deficiency in children. Magnetic Resonance Imaging (MRI) of the brain detects structural pituitary anomalies associated with GH deficiency. The prevalence of MRI abnormalities in patients with GHD, ranging from 25.9–100.0%. The Growth Hormone Research Society currently recommends that an MRI of the brain, with particular attention to the hypothalamic–pituitary region, should be carried out in any chi...